Each sachet contains

Active Ingredients	Amount
Magnesium oxide	300 mg

This product is gluten-free, sugar-free with a lemon flavor.

Take one sachet daily after a meal or as directed by your physician.

Pour the entire contents of the sachet onto your tongue, allow the powder to dissolve completely in your mouth, and then swallow

Packaging and Dosage Form:

Each package contains 20 sachets as granules that readily melt in the mouth.

Therapeutic and pharmacological effects:

Magnesium is an essential nutrient that acts as a cofactor in over 300 enzymatic systems. It is necessary for the formation of cyclic AMP (cAMP), calcium and magnesium ion transport across cell membranes, nerve signal transmission at neuromuscular junctions, proper muscle function (muscle contraction), carbohydrate, protein, and fat metabolism, tissue formation, and the development and maintenance of bones and teeth. Magnesium regulates numerous biochemical reactions in the body, including protein synthesis, nerve and muscle function, blood sugar control, and blood pressure regulation.

Magnesium has inhibitory effects on nerves and smooth muscles, leading to analgesic properties and reducing symptoms associated with migraines, post-surgical pain, neuropathic pain (pain caused by nerve damage), the rare erythromelalgia syndrome (a peripheral vascular disorder causing burning, pain, and redness, primarily in the feet), Raynaud’s phenomenon (spasms in small arteries of extremities, leading to reduced blood flow, coldness, numbness, and pale or bluish discoloration of fingers), and other vascular disorders and pain syndromes.

Side effects:

It is well tolerated at the recommended dose. Common side effects include gastrointestinal discomfort, nausea, vomiting, and diarrhea. Excessive consumption may lead to hypermagnesemia, characterized by symptoms such as low blood pressure, drowsiness, confusion, diminished tendon reflexes, muscle weakness, respiratory depression, and cardiac arrhythmias.

Drug interactions:

When taking this product alongside quinolone antibiotics (ciprofloxacin, levofloxacin, ofloxacin), tetracycline antibiotics (doxycycline, minocycline), or bisphosphonates (alendronate, etidronate), ensure at least a 2-hour interval between doses.

Additionally, if you are using potassium-sparing diuretics (amiloride, spironolactone), aminoglycoside antibiotics (gentamicin, streptomycin, amikacin), or calcium channel blockers (nifedipine, amlodipine), consult your doctor or pharmacist before using this product.

Warnings and precautions:

If you have kidney disease (renal dysfunction) or contraindications to magnesium in your diet, consult your doctor before use.

Patients with neuromuscular disorders such as myasthenia gravis should be closely monitored if magnesium is prescribed.

Higher doses of magnesium should only be taken under a doctor’s prescription.

Contraindications:

There are no specific contraindications for this product.

Pregnancy and breastfeeding:

Consumption of doses less than 350 milligrams per day is considered safe for pregnant and breastfeeding women.

Storage conditions:

Store at a temperature below 25°C, away from light, moisture, and out of reach of children.